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RNA$70885$ - translation to English
![ochre]], proteins in blue. The active site is a small segment of rRNA, indicated in red.](https://commons.wikimedia.org/wiki/Special:FilePath/50S-subunit of the ribosome 3CC2.png?width=200 "ochre]], proteins in blue. The active site is a small segment of rRNA, indicated in red.")
![[[Secondary structure]] of a [[telomerase RNA]].](https://commons.wikimedia.org/wiki/Special:FilePath/Ciliate telomerase RNA.JPG?width=200 "[[Secondary structure]] of a [[telomerase RNA]].")
![Structure of a [[hammerhead ribozyme]], a ribozyme that cuts RNA](https://commons.wikimedia.org/wiki/Special:FilePath/Full length hammerhead ribozyme.png?width=200 "Structure of a [[hammerhead ribozyme]], a ribozyme that cuts RNA")
![Watson-Crick base pairs in a [[siRNA]] (hydrogen atoms are not shown)](https://commons.wikimedia.org/wiki/Special:FilePath/Piwi-siRNA-basepairing.png?width=200 "Watson-Crick base pairs in a [[siRNA]] (hydrogen atoms are not shown)")
![A hairpin loop from a pre-mRNA. Highlighted are the [[nucleobase]]s (green) and the ribose-phosphate backbone (blue). This is a single strand of RNA that folds back upon itself.](https://commons.wikimedia.org/wiki/Special:FilePath/Pre-mRNA-1ysv-tubes.png?width=200 "A hairpin loop from a pre-mRNA. Highlighted are the [[nucleobase]]s (green) and the ribose-phosphate backbone (blue). This is a single strand of RNA that folds back upon itself.")
![Swiss]] [[scientist]] [[Friedrich Miescher]] discovered nucleic acid first naming it as nuclein, in 1868. Later, he raised the idea that it could be involved in [[heredity]].<ref>[[Bill Bryson]], ''[[A Short History of Nearly Everything]]'', Broadway Books, 2015.p. 500.</ref>](https://commons.wikimedia.org/wiki/Special:FilePath/Friedrich Miescher.jpg?width=200 "Swiss]] [[scientist]] [[Friedrich Miescher]] discovered nucleic acid first naming it as nuclein, in 1868. Later, he raised the idea that it could be involved in [[heredity]].<ref>[[Bill Bryson]], ''[[A Short History of Nearly Everything]]'', Broadway Books, 2015.p. 500.</ref>")
Wikipedia
The OmrA-B RNA gene family (also known as SraE RNA, RygA and RygB and OmrA and OmrB) is a pair of homologous OmpR-regulated small non-coding RNA that was discovered in E. coli during two large-scale screens. OmrA-B is highly abundant in stationary phase, but low levels could be detected in exponentially growing cells as well. RygB is adjacent to RygA a closely related RNA. These RNAs bind to the Hfq protein and regulate gene expression by antisense binding. They negatively regulate the expression of several genes encoding outer membrane proteins, including cirA, CsgD, fecA, fepA and ompT by binding in the vicinity of the Shine-Dalgarno sequence, suggesting the control of these targets is dependent on Hfq protein and RNase E. Taken together, these data suggest that OmrA-B participates in the regulation of outer membrane composition, responding to environmental conditions.
Together with the RNA chaperone Hfq, OmrA-B positively controls bacterial motility and negatively controls the production of acidic exopolysaccharide amylovoran in plant pathogen Erwinia amylovora.
